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Replimune’s (REPL) investment thesis changed dramatically this week after the FDA rejected its lead cancer therapy, RP1, for a second time, sending shares down approximately 64% and forcing management into cost-cutting mode. The market is now questioning whether RP1 can still win approval and whether Replimune has enough capital to withstand a prolonged setback if […]

As the economy struggles, and many Americans look for ways to save money, Costco has proven resilient. The chain has continued to grow its membership and retain nearly 90% of its members worldwide, “At Q2 end, we had 40.4 million paid executive memberships, up 9.5% versus last year. We ended the quarter with 82.1 million

Markets have been under pressure for weeks. Sentiment has turned. Most investors have already de-risked. That is exactly when JPMorgan chose to publish its latest note. In a note published April 13, JPMorgan strategist Mislav Matejka laid out the bank’s clearest position yet on what investors should be doing right now, arguing that conditions support

Most investors spend hours researching which stocks to buy or which funds to hold, yet they rarely ask a more fundamental question about placement. You could own the perfect mix of stocks, bonds, and index funds and still lose money to the IRS every year. The issue is not what you own, but where you

The Great U.S. blockade of shipping in and out of Iran is ending its first day, and you would be correct if you’re seeing little effect on your daily life. That’s neither good news nor bad news. It was only the first day. The drama still lies ahead. If you got gason April 13, your

Amazon.com is heading into a crucial earnings moment. With that, one of Wall Street’s most influential voices just made a subtle but important move. Goldman Sachs lowered its price target on Amazon stock to $275 from $280, while maintaining a Buy rating ahead of the company’s expected earnings report on April 30, 2026.  The revision

TheStreet aims to feature only the best products and services. If you buy something via one of our links, we may earn a commission. Why we love this deal Storage around the house is a valuable commodity. This is especially true during the spring cleaning season. Whether you want to stow rarely used holiday china

Market selloffs have a way of turning confident investors into anxious ones, and the 2026 trading year is delivering plenty of reasons to feel uneasy. The S&P 500 is down roughly 4% year-to-date, weighed down by geopolitical tensions, sticky inflation, and fading optimism about rate cuts. Fidelity Investments, which manages more than $5.8 trillion in

With the last two decades bringing significant changes to how travelers book their travel, many agencies outside specific niches struggle to stay afloat in a challenging market. Agencies that collapsed in bankruptcy over the last year include British firms Great Little Escapes and Jetline, Swedish travel company MixxTravel and French cruise operator Expedis Exploration. In two

Looking up at the mirror every day helps us slowly adjust to our natural aging process. If we were to look in the mirror once every five or ten years, we’ll be shocked by the changes time has drawn on our faces, despite all sorts of “magic” creams, moisturizers and serums. Nonetheless, slowing down aging